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Recent case reports, meta-analyses, and most recently, the breakthrough of 2 novel randomized controlled trials have shown DOACs to be a promising treatment for LV thrombus. Contrarily, some retrospective cohort reviews suggest less .
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Except for 1 trial that specifically studied the effect of low-dose DOAC on LV thrombus, all studies in this scientific statement address full-dose anticoagulation, and suggested management strategies given should not be extrapolated to low-dose DOAC.
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